Phagocytosis checkpoints as new targets for cancer immunotherapy

Jiang W. et al. 2012. Nature Reviews Cancer. 19 (10), 568-586.

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Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells

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Disrupting LILRB4/APOE interaction by an efficacious humanized antibody reverses T-cell suppression and blocks AML development